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Dolly the sheep, born in Scotland in 1996, was the first mammal cloned from a cell taken from an adult animal.

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ScienceBiology

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Dolly was born on 5 July 1996 at the Roslin Institute near Edinburgh. A team led by Ian Wilmut and Keith Campbell used a method called somatic cell nuclear transfer: the nucleus, which holds the genetic material, of a mammary gland cell from a six-year-old ewe was placed into an egg cell whose own nucleus had been removed. Until then many scientists believed a specialised adult cell could not be turned back to build a whole new animal. The team named her after the singer Dolly Parton. Dolly had six lambs of her own. She was put down in February 2003, aged six, after developing a lung tumour caused by a virus common in sheep; she also had arthritis. Her preserved body is on display at the National Museum of Scotland.

Türkçe oku
Koyun Dolly, 1996'da İskoçya'da doğdu ve yetişkin bir hayvandan alınan bir hücreden klonlanan ilk memeli oldu.

Dolly, 5 Temmuz 1996'da Edinburgh yakınlarındaki Roslin Enstitüsü'nde doğdu. Ian Wilmut ile Keith Campbell'ın yönettiği ekip, somatik hücre çekirdek transferi denen yöntemi kullandı: Altı yaşındaki bir koyunun meme bezinden alınan bir hücrenin, genetik malzemeyi taşıyan çekirdeği, kendi çekirdeği çıkarılmış bir yumurta hücresine yerleştirildi. O güne kadar pek çok bilim insanı, görevi belirlenmiş yetişkin bir hücrenin geri döndürülüp bütün bir canlıyı oluşturamayacağına inanıyordu. Ekip ona şarkıcı Dolly Parton'ın adını verdi. Dolly altı kuzu doğurdu. Şubat 2003'te, altı yaşındayken, koyunlarda yaygın bir virüsün yol açtığı bir akciğer tümörü yüzünden uyutuldu; eklem iltihabı da vardı. Doldurulmuş bedeni bugün İskoçya Ulusal Müzesi'nde sergileniyor.

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Background reading: Dolly (sheep)
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