In 1925 relay teams of sled dogs carried diphtheria antitoxin 1,085 km across Alaska to save the town of Nome, cut off by winter ice. Twenty mushers and about 150 dogs made the run in five and a half days, in temperatures near −50°C.
Diphtheria is a bacterial throat infection that can suffocate children; the antitoxin neutralises the poison the bacteria make. Nome's doctor, Curtis Welch, had only an expired supply, and the open-cockpit aircraft of the day could not fly safely in such cold, so the serum went by train to Nenana and then by dog sled. The hardest leg fell to Leonhard Seppala and his twelve-year-old lead dog Togo, whose team covered about 420 km, including a crossing of the sea ice of Norton Sound in a gale. Balto led Gunnar Kaasen's team over the last 89 km into Nome, became famous, and has a statue in New York's Central Park. The Iditarod sled race commemorates the run.



